We recruited 19 male runners to test 16 pairs of running shoes on busy city streets and quiet snow-covered roads. With their help, we came to the conclusion that the Mizuno Wave Rider 21 is the best pair of neutral running shoes for most men. The decades-old model is well-suited for logging everyday miles, with a sole that provides good cushioning and bounce, and an upper that’s supportive and breathable. If a traditional neutral shoe isn’t your thing, no worries: We also have picks for runners who prefer stability or low-drop running shoes.